BDBM50155378 (+/-)-1-(1-(4-fluorophenyl)-2-{4-[4-(2-methoxy-1-naphthyl)butyl]piperazin-1-yl}ethyl)-4-methylpiperazine::1-[2-(4-fluorophenyl)-2-(4-methylhexahydro-1-pyrazinyl)ethyl]-4-[4-(2-methoxy-1-naphthyl)butyl]hexahydropyrazine::CHEMBL433574

SMILES COc1ccc2ccccc2c1CCCCN1CCN(CC(N2CCN(C)CC2)c2ccc(F)cc2)CC1

InChI Key InChIKey=KLYBPNHUSHFSOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155378   

TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155378(1-[2-(4-fluorophenyl)-2-(4-methylhexahydro-1-pyraz...)
Affinity DataIC50: 7.90nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155378(1-[2-(4-fluorophenyl)-2-(4-methylhexahydro-1-pyraz...)
Affinity DataIC50: 57.3nMAssay Description:Displacement of [125I]Nle4-D-Phe7-alpha-MSH from human MC4 receptor expressed in COS1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed