BDBM50155559 1-(4-Dimethylamino-phenyl)-3-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-urea::CHEMBL184709

SMILES CN(C)c1ccc(NC(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc1

InChI Key InChIKey=LTXKLPPWYOFXIO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155559   

TargetTyrosine-protein kinase ABL1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155559(1-(4-Dimethylamino-phenyl)-3-[4-methyl-3-(4-pyridi...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory concentration required to inhibit Abl tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBreakpoint cluster region protein(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50155559(1-(4-Dimethylamino-phenyl)-3-[4-methyl-3-(4-pyridi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration required to inhibit Bcr-Abl tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
The First People'S Hospital of Hangzhou

Curated by ChEMBL
LigandPNGBDBM50155559(1-(4-Dimethylamino-phenyl)-3-[4-methyl-3-(4-pyridi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed