BDBM50155606 3-Butyl-1,2,3,4,5,6-hexahydro-benzo[f]isoquinoline::CHEMBL188713::CHEMBL541299

SMILES CCCCN1CCC2=C(CCc3ccccc23)C1

InChI Key InChIKey=VXQVYBORCSUFDN-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155606   

TargetSigma non-opioid intracellular receptor 1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155606(CHEMBL541299 | CHEMBL188713 | 3-Butyl-1,2,3,4,5,6-...)
Affinity DataIC50: 7.60nMAssay Description:In vitro for the binding affinity against sigma receptor by using [3H]DTG as radioligand in guinea pig cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50155606(CHEMBL541299 | CHEMBL188713 | 3-Butyl-1,2,3,4,5,6-...)
Affinity DataKi:  25nMAssay Description:Binding affinity towards dopamine D3 receptor in ventral striatal membranes of sprague-dawley rat brain by using [3H]-PD 128907 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155606(CHEMBL541299 | CHEMBL188713 | 3-Butyl-1,2,3,4,5,6-...)
Affinity DataIC50: 63nMAssay Description:Inhibition of [3H](-)-sulpiride binding to rat striatum dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed