BDBM50155855 (Z)-4-(Ethoxycarbonylmethyl-methyl-amino)-3-phenyl-pent-2-enoic acid ethyl ester::CHEMBL366270

SMILES CCOC(=O)CN(C)C(C)C(=C/C(=O)OCC)\c1ccccc1

InChI Key InChIKey=CBFVBEMCWJYACH-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50155855   

TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Budapest University of Technology and Economics

Curated by ChEMBL
LigandPNGBDBM50155855((Z)-4-(Ethoxycarbonylmethyl-methyl-amino)-3-phenyl...)
Affinity DataIC50: 2.18E+3nMAssay Description:H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Budapest University of Technology and Economics

Curated by ChEMBL
LigandPNGBDBM50155855((Z)-4-(Ethoxycarbonylmethyl-methyl-amino)-3-phenyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Budapest University of Technology and Economics

Curated by ChEMBL
LigandPNGBDBM50155855((Z)-4-(Ethoxycarbonylmethyl-methyl-amino)-3-phenyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Budapest University of Technology and Economics

Curated by ChEMBL
LigandPNGBDBM50155855((Z)-4-(Ethoxycarbonylmethyl-methyl-amino)-3-phenyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:H-bonding interaction between amino acid residue (Ser-133) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Budapest University of Technology and Economics

Curated by ChEMBL
LigandPNGBDBM50155855((Z)-4-(Ethoxycarbonylmethyl-methyl-amino)-3-phenyl...)
Affinity DataIC50: 2.68E+3nMAssay Description:H-bonding interaction between amino acid residue (Thr-89) of Sodium- and chloride-dependent GABA transporter 1TM2 and compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Budapest University of Technology and Economics

Curated by ChEMBL
LigandPNGBDBM50155855((Z)-4-(Ethoxycarbonylmethyl-methyl-amino)-3-phenyl...)
Affinity DataIC50: 2.68E+3nMAssay Description:H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Budapest University of Technology and Economics

Curated by ChEMBL
LigandPNGBDBM50155855((Z)-4-(Ethoxycarbonylmethyl-methyl-amino)-3-phenyl...)
Affinity DataIC50: 2.68E+3nMAssay Description:H-bonding interaction between amino acid residue (Thr-89) of Sodium- and chloride-dependent GABA transporter 1TM2 and compoundMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Budapest University of Technology and Economics

Curated by ChEMBL
LigandPNGBDBM50155855((Z)-4-(Ethoxycarbonylmethyl-methyl-amino)-3-phenyl...)
Affinity DataIC50: 3.17E+3nMAssay Description:H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Budapest University of Technology and Economics

Curated by ChEMBL
LigandPNGBDBM50155855((Z)-4-(Ethoxycarbonylmethyl-methyl-amino)-3-phenyl...)
Affinity DataIC50: 3.17E+3nMAssay Description:H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 1(Rat)
Budapest University of Technology and Economics

Curated by ChEMBL
LigandPNGBDBM50155855((Z)-4-(Ethoxycarbonylmethyl-methyl-amino)-3-phenyl...)
Affinity DataIC50: 3.17E+3nMAssay Description:H-bonding interaction between amino acid residue (Tyr-140) of Sodium- and chloride-dependent GABA transporter 1TM3 and compound was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed