BDBM50155970 4-(2,4-Dichloro-phenyl)-8-(2-methoxy-butylamino)-6-methyl-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-one; TFA::CHEMBL365868

SMILES CCC(CNc1cc(C)nc2N(CC(=O)Nc12)c1ccc(Cl)cc1Cl)OC

InChI Key InChIKey=ZLFWFBXVOFGYID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155970   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50155970(4-(2,4-Dichloro-phenyl)-8-(2-methoxy-butylamino)-6...)
Affinity DataIC50: 68nMAssay Description:Inhibition of [125I]ovine-CRF binding to corticotropin releasing factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed