BDBM50156247 CHEMBL186196::Thiophene-2-sulfonic acid (3-{(R)-2-[(R)-2-(7-ethoxy-1H-indol-3-yl)-1-methyl-ethylamino]-1-hydroxy-ethyl}-phenyl)-amide

SMILES CCOc1cccc2c(C[C@@H](C)NC[C@H](O)c3cccc(NS(=O)(=O)c4cccs4)c3)c[nH]c12

InChI Key InChIKey=HPWOVHXZFXEIOB-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50156247   

TargetBeta-3 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50156247(Thiophene-2-sulfonic acid (3-{(R)-2-[(R)-2-(7-etho...)
Affinity DataEC50:  1nMAssay Description:Binding inhibition constant was determined by inhibition of [125I]iodocyanopindolol binding to Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50156247(Thiophene-2-sulfonic acid (3-{(R)-2-[(R)-2-(7-etho...)
Affinity DataEC50:  7.70nMAssay Description:Agonistic activity was determined by measuring cAMP accumulation in CHO cells expressing cloned human Beta-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed