BDBM50157073 2-[(4R)-4-[(2S,18R)-6-[(3-{[(2S)-2-(6-methoxynaphthalen-2-yl)propanoyl]oxy}phenyl)methyl]-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.0^{2,10}.0^{4,8}.0^{14,18}]icosa-4,7-dien-17-yl]pentanamido]acetic acid::CHEMBL182965

SMILES COc1ccc2cc(ccc2c1)[C@H](C)C(=O)Oc1cccc(Cn2cc3C[C@@]4(C)C(CCC5C6CCC([C@H](C)CCC(=O)NCC(O)=O)[C@@]6(C)CCC45)Cc3n2)c1

InChI Key InChIKey=CBBNFKIUOKXJCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157073   

TargetSodium/bile acid cotransporter(Human)
Xenoport

Curated by ChEMBL
LigandPNGBDBM50157073(2-[(4R)-4-[(2S,18R)-6-[(3-{[(2S)-2-(6-methoxynapht...)
Affinity DataIC50: 6.30E+4nMAssay Description:In vitro inhibition of taurocholate binding to liver bile acid transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIleal sodium/bile acid cotransporter(Human)
Xenoport

Curated by ChEMBL
LigandPNGBDBM50157073(2-[(4R)-4-[(2S,18R)-6-[(3-{[(2S)-2-(6-methoxynapht...)
Affinity DataIC50: 3.00E+5nMAssay Description:In vitro inhibition of taurocholate binding to human ileal bile acid transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed