BDBM50157315 (S)-4-Methyl-piperazine-2-carboxylic acid [(S)-2-(4-tert-butylcarbamoyl-4-cyclohexyl-piperidin-1-yl)-1-(4-fluoro-benzyl)-2-oxo-ethyl]-amide; dihydrochloride::CHEMBL3216393

SMILES CN1CCNC[C@H]1C(=O)N[C@H](Cc1ccc(F)cc1)C(=O)N1CCC(CC1)(C1CCCCC1)C(=O)NC(C)(C)C

InChI Key InChIKey=AQQUROKWABNSSB-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50157315   

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157315((S)-4-Methyl-piperazine-2-carboxylic acid [(S)-2-(...)
Affinity DataEC50:  29nMAssay Description:Effective concentration towards human melanocortin-4 receptor mediated cAMP accumulation in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157315((S)-4-Methyl-piperazine-2-carboxylic acid [(S)-2-(...)
Affinity DataIC50: 87nMAssay Description:Concentration for 50% inhibition of human melanocortin-4 receptor expressed in CHO cells using [125I]NDP-alpha-MSH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157315((S)-4-Methyl-piperazine-2-carboxylic acid [(S)-2-(...)
Affinity DataEC50:  2.90E+3nMAssay Description:Effective concentration towards human melanocortin-3 receptor mediated cAMP accumulation in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157315((S)-4-Methyl-piperazine-2-carboxylic acid [(S)-2-(...)
Affinity DataEC50:  3.30E+3nMAssay Description:Effective concentration towards human melanocortin-5 receptor mediated cAMP accumulation in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed