BDBM50158194 1-[2,2-bis(4-methylphenyl)vinyl]-4-(methylsulfonyl)benzene::CHEMBL179204

SMILES [#6]-c1ccc(cc1)-[#6](=[#6]/c1ccc(cc1)S([#6])(=O)=O)\c1ccc(-[#6])cc1

InChI Key InChIKey=ILBFVLJVNCRESL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50158194   

TargetProstaglandin G/H synthase 2(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50158194(1-[2,2-bis(4-methylphenyl)vinyl]-4-(methylsulfonyl...)
Affinity DataIC50: 3.10E+4nMAssay Description:In vitro inhibitory concentration against ovine Cyclooxygenase-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50158194(1-[2,2-bis(4-methylphenyl)vinyl]-4-(methylsulfonyl...)
Affinity DataIC50: 3.10E+4nMAssay Description:In vitro inhibitory concentration against ovine Cyclooxygenase-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50158194(1-[2,2-bis(4-methylphenyl)vinyl]-4-(methylsulfonyl...)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50158194(1-[2,2-bis(4-methylphenyl)vinyl]-4-(methylsulfonyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration against ovine Cyclooxygenase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50158194(1-[2,2-bis(4-methylphenyl)vinyl]-4-(methylsulfonyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibitory concentration against ovine Cyclooxygenase-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed