BDBM50158438 CHEMBL225092::N-[3-(4-methoxyphenoxy)-4-pyridinyl]trifluoromethanesulfonamide

SMILES COc1ccc(Oc2cnccc2NS(=O)(=O)C(F)(F)F)cc1

InChI Key InChIKey=MDPRFMFQKOLHCO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158438   

TargetProstaglandin G/H synthase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50158438(N-[3-(4-methoxyphenoxy)-4-pyridinyl]trifluorometha...)
Affinity DataIC50: 260nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50158438(N-[3-(4-methoxyphenoxy)-4-pyridinyl]trifluorometha...)
Affinity DataIC50: 440nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed