BDBM50158441 CHEMBL224693::N-[3-(3-chlorophenoxy)-4-pyridinyl]trifluoromethanesulfonamide

SMILES FC(F)(F)S(=O)(=O)Nc1ccncc1Oc1cccc(Cl)c1

InChI Key InChIKey=DBTIALADKQUNTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158441   

TargetProstaglandin G/H synthase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50158441(N-[3-(3-chlorophenoxy)-4-pyridinyl]trifluoromethan...)
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50158441(N-[3-(3-chlorophenoxy)-4-pyridinyl]trifluoromethan...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed