BDBM50158442 CHEMBL224193::N-[3-(4-bromophenoxy)-4-pyridinyl]methanesulfonamide

SMILES CS(=O)(=O)Nc1ccncc1Oc1ccc(Br)cc1

InChI Key InChIKey=POERZTJYPCMFQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50158442   

TargetProstaglandin G/H synthase 1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50158442(N-[3-(4-bromophenoxy)-4-pyridinyl]methanesulfonami...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of COX1 in human whole blood assessed as inhibition of calcium ionophore A-23187-stimulated platelet aggregation by measuring TXB2 product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50158442(N-[3-(4-bromophenoxy)-4-pyridinyl]methanesulfonami...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of COX2 in human whole blood assessed as inhibition of LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed