BDBM50158505 CHEMBL3786100

SMILES Nc1ncnc2n(cc(-c3cc(OCC45CCC(CC4)O5)ccc3F)c12)[C@@H]1C[C@H](CN2CC[S+]([O-])CC2)C1

InChI Key InChIKey=JAXCPMZZRNLZBU-ITXHVEOOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50158505   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50158505(CHEMBL3786100)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of full length IGF-1 receptor (unknown origin) transfected in Ba/F3 cells assessed as cell proliferationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50158505(CHEMBL3786100)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of full length IGF-1 receptor (unknown origin) autophosphorylation transfected in HEK293 cells pretreated for 60 mins followed by IGF-1 st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50158505(CHEMBL3786100)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of IGF-1 receptor (unknown origin) in presence of [gamma33P]ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed