BDBM50159005 2-(4-Benzyl-piperidin-1-ylmethyl)-3,4-dihydro-2H-naphthalen-1-one::CHEMBL434905

SMILES O=C1C(CN2CCC(Cc3ccccc3)CC2)CCc2ccccc12

InChI Key InChIKey=LTCASCAKDDGTLO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50159005   

TargetSigma non-opioid intracellular receptor 1(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50159005(2-(4-Benzyl-piperidin-1-ylmethyl)-3,4-dihydro-2H-n...)
Affinity DataKi:  3.38nMAssay Description:Inhibitory constant against sigma receptor type 2 using 3 nM [3H]ditolylguanidineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50159005(2-(4-Benzyl-piperidin-1-ylmethyl)-3,4-dihydro-2H-n...)
Affinity DataKi:  24nMAssay Description:Inhibitory constant against sigma receptor type 1 using 3 nM [3H]pentazocineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50159005(2-(4-Benzyl-piperidin-1-ylmethyl)-3,4-dihydro-2H-n...)
Affinity DataKi:  260nMAssay Description:Inhibitory constant was determined against 5-hydroxytryptamine 1A receptor using 1.2 nM [3H]8-OH-DPATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50159005(2-(4-Benzyl-piperidin-1-ylmethyl)-3,4-dihydro-2H-n...)
Affinity DataKi:  1.09E+3nMAssay Description:Inhibitory constant against dopamine D2 receptor using 0.2 nM [3H]-spiperoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed