BDBM50159368 (4R)-N'-methyl-N'-[(4-methylbenzene)sulfonyl]-1-(naphthalene-2-sulfonyl)-4-sulfanylpyrrolidine-2-carbohydrazide::CHEMBL425383

SMILES CN(NC(=O)C1C[C@@H](S)CN1S(=O)(=O)c1ccc2ccccc2c1)S(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=FJCTWYALBIKBLC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50159368   

TargetEndothelin-converting enzyme 1(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159368((4R)-N'-methyl-N'-[(4-methylbenzene)sulfonyl]-1-(n...)
Affinity DataIC50: 61.3nMAssay Description:Inhibitory concentration against human ECE-1 by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159368((4R)-N'-methyl-N'-[(4-methylbenzene)sulfonyl]-1-(n...)
Affinity DataIC50: 2.53E+3nMAssay Description:Inhibitory concentration against human ECE-1 expressed in MDCK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159368((4R)-N'-methyl-N'-[(4-methylbenzene)sulfonyl]-1-(n...)
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibitory concentration against human angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetNeprilysin(Human)
University Institute of Pathology

Curated by ChEMBL
LigandPNGBDBM50159368((4R)-N'-methyl-N'-[(4-methylbenzene)sulfonyl]-1-(n...)
Affinity DataIC50: 3.92E+4nMAssay Description:Inhibitory concentration against NeprilysinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed