BDBM50159718 CHEMBL3787326

SMILES N[C@@H](CCCCNC(=O)[C@@H]1Cc2ccccc2CN1)C(=O)NCC(c1ccccc1)c1ccccc1

InChI Key InChIKey=BPYCTNYCWWGTQW-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159718   

TargetC-X-C chemokine receptor type 3(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50159718(CHEMBL3787326)
Affinity DataEC50:  158nMAssay Description:Positive allosteric modulation of ProLink1-tagged wild type CXCR3 (unknown origin) expressed in HEK293T cells assessed as beta-arrestin-2 recruitment...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50159718(CHEMBL3787326)
Affinity DataEC50:  282nMAssay Description:Positive allosteric modulation of ProLink2-tagged wild type CXCR3 (unknown origin) expressed in HEK293T cells assessed as beta-arrestin-2 recruitment...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 3(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50159718(CHEMBL3787326)
Affinity DataEC50:  2.24E+3nMAssay Description:Positive allosteric modulation of human CXCR3 expressed in HEK293T cell membranes after 30 mins by [35S]GTPgammaS incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details Article
PubMed