BDBM50159899 1-{1-[3-(2-Chloro-5-methyl-phenoxy)-3-cyclohexyl-2-hydroxy-propyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL264288

SMILES Cc1ccc(Cl)c(OC(C(O)CN2CCC(CC2)n2c3ccccc3[nH]c2=O)C2CCCCC2)c1

InChI Key InChIKey=WUADNUGCSVGPSQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50159899   

TargetMu-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50159899(1-{1-[3-(2-Chloro-5-methyl-phenoxy)-3-cyclohexyl-2...)
Affinity DataKi:  103nMAssay Description:Binding affinity towards human opioid receptor mu 1 was determined by using [3H]diprenorphine as radioligand expressed in Chinese hamster ovary (CHO)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50159899(1-{1-[3-(2-Chloro-5-methyl-phenoxy)-3-cyclohexyl-2...)
Affinity DataKi:  462nMAssay Description:Binding affinity towards human opioid receptor like 1 was determined by using [3H]nociceptin as radioligand expressed in Chinese hamster ovary (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed