BDBM50159903 1-{1-[3-(2-Chloro-5-methoxy-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL262104

SMILES COc1ccc(Cl)c(OC(CCN2CCC(CC2)n2c3ccccc3[nH]c2=O)C(C)C)c1

InChI Key InChIKey=ROFZYAIHNKKOTB-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159903   

TargetNociceptin receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50159903(1-{1-[3-(2-Chloro-5-methoxy-phenoxy)-4-methyl-pent...)
Affinity DataKi:  3nMAssay Description:Binding affinity towards human opioid receptor like 1 was determined by using [3H]-nociceptin as radioligand expressed in Chinese hamster ovary (CHO)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50159903(1-{1-[3-(2-Chloro-5-methoxy-phenoxy)-4-methyl-pent...)
Affinity DataKi:  58nMAssay Description:Binding affinity towards human opioid receptor mu 1 was determined by using [3H]-diprenorphine as radioligand expressed in Chinese hamster ovary (CHO...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50159903(1-{1-[3-(2-Chloro-5-methoxy-phenoxy)-4-methyl-pent...)
Affinity DataIC50:  80nMAssay Description:Inhibitory concentration measured by cellular decreases in forskolin stimulated cAMP in CHO cells stably transfected with hORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed