BDBM50159914 1-{1-[4-Methyl-3-(5-methyl-2-nitro-phenoxy)-pentyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL182202

SMILES CC(C)C(CCN1CCC(CC1)n1c2ccccc2[n-]c1=[OH+])Oc1cc(C)ccc1[N+]([O-])=O

InChI Key InChIKey=ZUZLFJYQRAAUJT-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159914   

TargetNociceptin receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50159914(1-{1-[4-Methyl-3-(5-methyl-2-nitro-phenoxy)-pentyl...)
Affinity DataKi:  39nMAssay Description:Binding affinity towards human opioid receptor like 1 was determined by using [3H]nociceptin as radioligand expressed in Chinese hamster ovary (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50159914(1-{1-[4-Methyl-3-(5-methyl-2-nitro-phenoxy)-pentyl...)
Affinity DataKi:  62nMAssay Description:Binding affinity towards human opioid receptor mu 1 was determined by using [3H]diprenorphine as radioligand expressed in Chinese hamster ovary (CHO)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50159914(1-{1-[4-Methyl-3-(5-methyl-2-nitro-phenoxy)-pentyl...)
Affinity DataIC50: 165nMAssay Description:Inhibitory concentration measured by cellular decreases in forskolin stimulated cAMP in CHO cells stably transfected with hORL1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed