BDBM50159915 1-{1-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxy-hexyl]-piperidin-4-yl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL182410

SMILES CCCC(Oc1cc(C)ccc1Cl)C(O)CN1CCC(CC1)n1c2ccccc2[nH]c1=O

InChI Key InChIKey=AZPDSENEWXRPQS-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50159915   

TargetNociceptin receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50159915(1-{1-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxy-hexy...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards human opioid receptor like 1 was determined by using [3H]nociceptin as radioligand expressed in Chinese hamster ovary (CHO) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50159915(1-{1-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxy-hexy...)
Affinity DataKi:  27nMAssay Description:Binding affinity towards human opioid receptor mu 1 was determined by using [3H]diprenorphine as radioligand expressed in Chinese hamster ovary (CHO)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50159915(1-{1-[3-(2-Chloro-5-methyl-phenoxy)-2-hydroxy-hexy...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibitory concentration measured by cellular decreases in forskolin stimulated cAMP in CHO cells stably transfected with hORL1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed