BDBM50160808 4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,6,7,8,9,10-hexahydro-cycloocta[b]pyridin-8-ol::CHEMBL360457

SMILES CCN1CCN(CC1)c1cc(-c2ccc(F)cc2)c2CCC[C@@H](O)CCc2n1

InChI Key InChIKey=FLPVFOMJIXWGPC-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50160808   

TargetD(2) dopamine receptor(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50160808(4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...)
Affinity DataKi:  3.60nMAssay Description:In vitro binding affinity against recombinant human dopamine receptor D2L in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Dainippon Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50160808(4-(4-Fluoro-phenyl)-2-(4-propyl-piperazin-1-yl)-5,...)
Affinity DataKi:  9.67nMAssay Description:In vitro binding affinity against recombinant human 5-hydroxytryptamine 2A receptor in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed