BDBM50160828 CHEMBL366925::N-hydroxycarbamate derivative

SMILES COC(=O)N(O)CCC#Cc1ccc(OCCCCN2CCN(CC2)C(c2ccc(F)cc2)c2ccc(F)cc2)cc1

InChI Key InChIKey=QNNXKPSMUIHGIZ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50160828   

TargetHistamine H1 receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50160828(N-hydroxycarbamate derivative | CHEMBL366925)
Affinity DataKi:  5.01nMAssay Description:Binding affinity for human Histamine H1 receptor in CHO K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50160828(N-hydroxycarbamate derivative | CHEMBL366925)
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration against 5-lipoxygenase in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50160828(N-hydroxycarbamate derivative | CHEMBL366925)
Affinity DataIC50: 170nMAssay Description:Inhibitory concentration against human 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed