BDBM50160901 CHEMBL179451::N*6*-(2-Chloro-ethyl)-N*4*-(3-chloro-phenyl)-quinazoline-4,6-diamine

SMILES ClCCNc1ccc2ncnc(Nc3cccc(Cl)c3)c2c1

InChI Key InChIKey=RGZBNUZXRSSFQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50160901   

TargetEpidermal growth factor receptor(Human)
Mcgill University/Royal Victoria Hospital

Curated by ChEMBL
LigandPNGBDBM50160901(N*6*-(2-Chloro-ethyl)-N*4*-(3-chloro-phenyl)-quina...)
Affinity DataIC50: 26nMAssay Description:Inhibition of poly(L-glutamic acid-L-tyrosine) phosphorylation by EGFR tyrosine kinase of A431 carcinoma cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed