BDBM50161489 CHEMBL182148::N-{3-Cyano-6-[methyl-(1,2,3,4-tetrahydro-naphthalen-1-yl)-amino]-4,5,6,7-tetrahydro-benzo[b]thiophen-2-yl}-2-ethyl-butyramide

SMILES CCC(CC)C(=O)Nc1sc2CC(CCc2c1C#N)N(C)C1CCCc2ccccc12

InChI Key InChIKey=FRZRQGVRAANXRI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50161489   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161489(N-{3-Cyano-6-[methyl-(1,2,3,4-tetrahydro-naphthale...)
Affinity DataIC50: 139nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161489(N-{3-Cyano-6-[methyl-(1,2,3,4-tetrahydro-naphthale...)
Affinity DataIC50: 139nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161489(N-{3-Cyano-6-[methyl-(1,2,3,4-tetrahydro-naphthale...)
Affinity DataIC50: 158nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161489(N-{3-Cyano-6-[methyl-(1,2,3,4-tetrahydro-naphthale...)
Affinity DataIC50: 158nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed