BDBM50161494 CHEMBL179281::N-[3-Cyano-6-(1,1-dimethyl-propyl)-4,5,6,7-tetrahydro-benzo[b]thiophen-2-yl]-2-ethyl-butyramide

SMILES CCC(CC)C(=O)Nc1sc2CC(CCc2c1C#N)C(C)(C)CC

InChI Key InChIKey=SWIBDWBSJSJQHL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161494   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161494(N-[3-Cyano-6-(1,1-dimethyl-propyl)-4,5,6,7-tetrahy...)
Affinity DataIC50: 129nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161494(N-[3-Cyano-6-(1,1-dimethyl-propyl)-4,5,6,7-tetrahy...)
Affinity DataIC50: 181nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed