BDBM50161497 CHEMBL178768::N-{3-Cyano-6-[(2,4-dichloro-benzyl)-isopropyl-amino]-4,5,6,7-tetrahydro-benzo[b]thiophen-2-yl}-2-ethyl-butyramide

SMILES CCC(CC)C(=O)Nc1sc2CC(CCc2c1C#N)N(Cc1ccc(Cl)cc1Cl)C(C)C

InChI Key InChIKey=LBUDISJZPKCKEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161497   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161497(N-{3-Cyano-6-[(2,4-dichloro-benzyl)-isopropyl-amin...)
Affinity DataIC50: 59nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161497(N-{3-Cyano-6-[(2,4-dichloro-benzyl)-isopropyl-amin...)
Affinity DataIC50: 129nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed