BDBM50161498 4-Cyano-5-(2-ethyl-butyrylamino)-3-methyl-thiophene-2-carboxylic acid (2,4-dichloro-benzyl)-isopropyl-amide::CHEMBL362657

SMILES CCC(CC)C(=O)Nc1sc(C(=O)N(Cc2ccc(Cl)cc2Cl)C(C)C)c(C)c1C#N

InChI Key InChIKey=SKAHOANFYMJREK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50161498   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161498(4-Cyano-5-(2-ethyl-butyrylamino)-3-methyl-thiophen...)
Affinity DataIC50: 41nMAssay Description:Inhibition of glucagon induced cAMP accumulation in human glucagon receptor transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50161498(4-Cyano-5-(2-ethyl-butyrylamino)-3-methyl-thiophen...)
Affinity DataIC50: 153nMAssay Description:Inhibitory concentration towards binding of [125I]glucagon to the human glucagon receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed