BDBM50162103 3-Cyclohexyl-1-(2-methanesulfonylamino-2-oxo-ethyl)-2-phenyl-1H-indole-6-carboxylic acid::CHEMBL361202

SMILES CS(=O)(=O)NC(=O)Cn1c(c(C2CCCCC2)c2ccc(cc12)C(O)=O)-c1ccccc1

InChI Key InChIKey=KSWXNZWMEVSGQP-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162103   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162103(3-Cyclohexyl-1-(2-methanesulfonylamino-2-oxo-ethyl...)
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Irbm (Merck Research Laboratories Rome)

Curated by ChEMBL
LigandPNGBDBM50162103(3-Cyclohexyl-1-(2-methanesulfonylamino-2-oxo-ethyl...)
Affinity DataEC50: >50nMAssay Description:Effective concentration to inhibit the activity of RNA dependent RNA polymerase nonstructural protein 5B in hepatitis C virus; n=1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed