BDBM50162522 (2S,4S,5R)-2-Isobutyl-5-thiophen-2-yl-1-(2-trifluoromethyl-benzoyl)-pyrrolidine-2,4-dicarboxylic acid::CHEMBL178443

SMILES CC(C)C[C@]1(C[C@@H]([C@@H](N1C(=O)c1ccccc1C(F)(F)F)c1cccs1)C(O)=O)C(O)=O

InChI Key InChIKey=GMRIQTRWKFWFGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50162522   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50162522((2S,4S,5R)-2-Isobutyl-5-thiophen-2-yl-1-(2-trifluo...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against Hepatitis C virus RNA dependent RNA polymerase Nonstructural protein 5BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed