BDBM50162597 1-benzyl-3-(1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1H-[1,8]naphthyridin-2-one::CHEMBL179943

SMILES Oc1c(C2=NS(=O)(=O)c3ccccc3N2)c(=O)n(Cc2ccccc2)c2ncccc12

InChI Key InChIKey=HNWWRJPHLDUXDN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50162597   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162597(1-benzyl-3-(1,1-dioxo-1,4-dihydro-1lambda*6*-benzo...)
Affinity DataIC50: 83nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B of genotype 1b Hepatitis C virusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162597(1-benzyl-3-(1,1-dioxo-1,4-dihydro-1lambda*6*-benzo...)
Affinity DataIC50: 83nMAssay Description:Inhibition of HCV 1b NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162597(1-benzyl-3-(1,1-dioxo-1,4-dihydro-1lambda*6*-benzo...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of HCV 1a NS5B RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed