BDBM50162606 3-(1,1-Dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]thiadiazin-3-yl)-4-hydroxy-1-(1-isopropyl-butylamino)-1H-quinolin-2-one::CHEMBL181246

SMILES CCCC(Nn1c2ccccc2c(O)c(C2=Nc3ccccc3S(=O)(=O)N2)c1=O)C(C)C

InChI Key InChIKey=IVQPKSRFLLILQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162606   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162606(3-(1,1-Dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]th...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B of genotype 1b Hepatitis C virusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50162606(3-(1,1-Dioxo-1,4-dihydro-1lambda*6*-benzo[1,2,4]th...)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibitory concentration against RNA dependent RNA polymerase Nonstructural protein 5B of genotype 1a Hepatitis C virusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed