BDBM50162731 1-Benzyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]diazepane-5-carboxylic acid hydroxyamide::1-benzyl-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-1,4-diazepane-5-carboxamide::CHEMBL183132

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(Cc2ccccc2)CCC1C(=O)NO

InChI Key InChIKey=CLTINYAXRIROMY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50162731   

TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162731(1-Benzyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]...)
Affinity DataIC50:  287nMAssay Description:Inhibitory concentration against matrix metalloproteinase-1 at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50162731(1-Benzyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50162731(1-Benzyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]...)
Affinity DataIC50:  83nMAssay Description:Inhibitory concentration against TNF-alpha converting enzyme at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50162731(1-Benzyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]...)
Affinity DataIC50:  7nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-13 at 1 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed