BDBM50164013 CHEMBL439846::Pyridine-3-sulfonic acid benzyl-[6-cyano-1-(3-methyl-3H-imidazol-4-ylmethyl)-1,2,3,4-tetrahydro-quinolin-3-yl]-amide
SMILES Cn1cncc1CN1CC(Cc2cc(ccc12)C#N)N(Cc1ccccc1)S(=O)(=O)c1cccnc1
InChI Key InChIKey=FUQQEQIALYIXCF-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50164013
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of cellular reversion in H-ras transformed Rat-1 cellsMore data for this Ligand-Target Pair
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human farnesyltransferaseMore data for this Ligand-Target Pair