BDBM50164123 6-(2-Chloro-phenyl)-2-[4-(2-diethylamino-ethoxy)-phenylamino]-5,8-dimethyl-8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL181017

SMILES CCN(CC)CCOc1ccc(Nc2ncc3c(C)c(-c4ccccc4Cl)c(=O)n(C)c3n2)cc1

InChI Key InChIKey=XPRLKGXPWFZGHU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164123   

TargetWee1-like protein kinase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50164123(6-(2-Chloro-phenyl)-2-[4-(2-diethylamino-ethoxy)-p...)
Affinity DataIC50: 550nMAssay Description:Inhibition of checkpoint kinase Wee1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50164123(6-(2-Chloro-phenyl)-2-[4-(2-diethylamino-ethoxy)-p...)
Affinity DataIC50: 550nMAssay Description:Inhibition of Wee1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50164123(6-(2-Chloro-phenyl)-2-[4-(2-diethylamino-ethoxy)-p...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of c-Src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed