BDBM50165802 (S)-6-[1-(2-Hydroxy-ethyl)-1,2,3,4-tetrahydro-quinolin-7-yloxymethyl]-1-{4-[3-(2-methoxy-benzyloxy)-propoxy]-phenyl}-piperazin-2-one::CHEMBL383181

SMILES COc1ccccc1COCCCOc1ccc(cc1)N1[C@H](COc2ccc3CCCN(CCO)c3c2)CNCC1=O

InChI Key InChIKey=QJCBDDQZSODRSU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50165802   

TargetRenin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165802((S)-6-[1-(2-Hydroxy-ethyl)-1,2,3,4-tetrahydro-quin...)
Affinity DataIC50: 33nMAssay Description:Concentration required to inhibit renin activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed