BDBM50166121 CHEMBL3797480

SMILES CCCCC(=O)Nc1ccc2NC(=O)\C(=C3/Nc4ccccc4/C/3=N\O)c2c1

InChI Key InChIKey=QSDUMEKQISKWQM-UHFFFAOYSA-N

Data  1 KI  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50166121   

TargetSerine/threonine-protein kinase 17B(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50166121(CHEMBL3797480)
Affinity DataKi:  0.260nMAssay Description:Competitive inhibition of DRAK2 (unknown origin) using MRLC3 peptide as substrate incubated for 2 hrs by Lineweaver-Burk plot analysis in presence of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 17B(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50166121(CHEMBL3797480)
Affinity DataIC50: 3nMAssay Description:Inhibition of DRAK2 (unknown origin) using MRLC3 peptide as substrate incubated for 2 hrs by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase 17A(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50166121(CHEMBL3797480)
Affinity DataIC50: 51nMAssay Description:Inhibition of DRAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetDeath-associated protein kinase 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50166121(CHEMBL3797480)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of DAPK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetDeath-associated protein kinase 3(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50166121(CHEMBL3797480)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of DAPK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetDeath-associated protein kinase 2(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50166121(CHEMBL3797480)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of DAPK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50166121(CHEMBL3797480)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALK (unknown origin) using peptide substrate incubated for 30 mins by europium donor dye-based plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50166121(CHEMBL3797480)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-MET (unknown origin) using peptide substrate incubated for 30 mins by europium donor dye-based plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50166121(CHEMBL3797480)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) using peptide substrate incubated for 30 mins by europium donor dye-based plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetMaternal embryonic leucine zipper kinase(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50166121(CHEMBL3797480)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MELK (unknown origin) using peptide substrate incubated for 30 mins by europium donor dye-based plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50166121(CHEMBL3797480)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IRK (unknown origin) using peptide substrate incubated for 30 mins by europium donor dye-based plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50166121(CHEMBL3797480)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (746 to 750) deletion mutant (unknown origin) using peptide substrate incubated for 30 mins by europium donor dye-based plate read...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetActivated CDC42 kinase 1(Human)
Korea Research Institute of Chemical Technology

Curated by ChEMBL
LigandPNGBDBM50166121(CHEMBL3797480)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AcK1 (unknown origin) using peptide substrate incubated for 30 mins by europium donor dye-based plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed