BDBM50166215 17-benzyloxy-10-hydroxy-4,13-dimethyl-(13R,17S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10-trien-14-one

SMILES CN1CC[C@]23c4c5O[C@@]2(C)C(=O)CC[C@@]3(OCc2ccccc2)C1Cc4ccc5O

InChI Key InChIKey=BROLKJHQMMXCRO-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50166215   

TargetMu-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166215(17-benzyloxy-10-hydroxy-4,13-dimethyl-(13R,17S)-12...)
Affinity DataKi:  0.180nMAssay Description:Inhibition of [3H]DAMGO binding to opioid receptor mu from rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166215(17-benzyloxy-10-hydroxy-4,13-dimethyl-(13R,17S)-12...)
Affinity DataIC50: 0.5nMAssay Description:In vitro agonistic activity against opioid receptor mu of guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166215(17-benzyloxy-10-hydroxy-4,13-dimethyl-(13R,17S)-12...)
Affinity DataIC50: 2.30nMAssay Description:In vitro agonistic activity against opioid receptor delta of mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166215(17-benzyloxy-10-hydroxy-4,13-dimethyl-(13R,17S)-12...)
Affinity DataKi:  2.46nMAssay Description:Inhibition of [3H]U-69593 binding to opioid receptor kappa from guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50166215(17-benzyloxy-10-hydroxy-4,13-dimethyl-(13R,17S)-12...)
Affinity DataKi:  3.67nMAssay Description:Inhibition of [3H][Ile5,6]deltorphin II binding to opioid receptor delta from rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed