BDBM50166285 (RS)-2-amino-3-[3-hydroxy-5-(2-propyl-2H-5-tetrazolyl)-4-isoxazolyl]propionic acid::2-Amino-3-[3-hydroxy-5-(2-propyl-2H-tetrazol-5-yl)-isoxazol-4-yl]-propionic acid::2-amino-3-(3-hydroxy-5-(2-propyl-2H-tetrazol-5-yl)isoxazol-4-yl)propanoic acid::CHEMBL372643
SMILES CCCn1nnc(n1)-c1o[nH]c(=O)c1CC(N)C(O)=O
InChI Key InChIKey=SFPCQXPSZCJTFF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50166285
Affinity DataKi: 0.730nMAssay Description:Displacement of [3H]AMPA from rat recombinant GluR4 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]AMPA from rat recombinant GluR3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]AMPA from rat recombinant GluR2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]AMPA from rat recombinant GluR1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Displacement of [3H]SYM 2081 from rat recombinant GluR5 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: >100nMAssay Description:Displacement of [3H]KA from rat recombinant GluR6 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 732nMAssay Description:Binding affinity for ionotropic Glutamate receptor AMPA 4 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.18E+3nMAssay Description:Binding affinity for ionotropic Glutamate receptor AMPA 3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.61E+3nMAssay Description:Binding affinity for ionotropic Glutamate receptor AMPA 2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.15E+3nMAssay Description:Binding affinity for ionotropic Glutamate receptor AMPA 1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 1(Human)
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 5.45E+3nMAssay Description:Binding affinity for kainate Glutamate receptor GluR5 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Human)
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity for kainate Glutamate receptor GluR6 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 3(Rat)
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
The Danish University of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 3.20E+4nMAssay Description:In vitro activity of the compound at Ionotropic glutamate receptor using cortical wedge assays in rat brain synaptosomaMore data for this Ligand-Target Pair
Affinity DataEC50: 7.90E+4nMAssay Description:Agonist activity at GluR4 expressed in HEK293 cells by Fluo-4/Ca2+ assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.50E+5nMAssay Description:Agonist activity at GluR3 expressed in HEK293 cells by Fluo-4/Ca2+ assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.80E+5nMAssay Description:Agonist activity at GluR1 expressed in HEK293 cells by Fluo-4/Ca2+ assayMore data for this Ligand-Target Pair
Affinity DataEC50: 8.30E+5nMAssay Description:Agonist activity at GluR2Q expressed in HEK293 cells by Fluo-4/Ca2+ assayMore data for this Ligand-Target Pair