BDBM50166337 9-[3-(3,4-Difluoro-phenyl)-prop-2-yn-(Z)-ylidene]-7-aza-tricyclo[4.3.1.0*3,7*]decane-2-carboxylic acid methyl ester::CHEMBL194439

SMILES COC(=O)C1C2CCC3CC1\C(CN23)=C\C#Cc1ccc(F)c(F)c1

InChI Key

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50166337   

TargetSodium-dependent serotonin transporter(Rat)
Acenta Discovery

Curated by ChEMBL
LigandPNGBDBM50166337(9-[3-(3,4-Difluoro-phenyl)-prop-2-yn-(Z)-ylidene]-...)
Affinity DataKi:  69nMAssay Description:Inhibitory constant against reuptake of [3H]5-HT at serotonin transporter of rat midbrain cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransporter(Rat)
Acenta Discovery

Curated by ChEMBL
LigandPNGBDBM50166337(9-[3-(3,4-Difluoro-phenyl)-prop-2-yn-(Z)-ylidene]-...)
Affinity DataKi:  110nMAssay Description:Inhibitory constant against reuptake of [3H]NE at norepinephrine transporter of rat parietal-occipital cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Acenta Discovery

Curated by ChEMBL
LigandPNGBDBM50166337(9-[3-(3,4-Difluoro-phenyl)-prop-2-yn-(Z)-ylidene]-...)
Affinity DataKi:  3.15E+3nMAssay Description:Inhibitory constant against reuptake of [3H]-DA at dopamine transporter of rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed