BDBM50166640 CHEMBL195298::N*4*-(2,4-Dichloro-benzyl)-N*2*-(4-diethylamino-1-methyl-butyl)-pyrimidine-2,4-diamine

SMILES CCN(CC)CCCC(C)Nc1nccc(NCc2ccc(Cl)cc2Cl)n1

InChI Key InChIKey=STXUPEUBCKDDQA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50166640   

TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50166640(N*4*-(2,4-Dichloro-benzyl)-N*2*-(4-diethylamino-1-...)
Affinity DataIC50: 270nMAssay Description:Inhibitory concentration against human C-C chemokine receptor type 4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50166640(N*4*-(2,4-Dichloro-benzyl)-N*2*-(4-diethylamino-1-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory concentration in CCR4-transfected murine pre-B L1.2 cells (chemotaxis assay)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50166640(N*4*-(2,4-Dichloro-benzyl)-N*2*-(4-diethylamino-1-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against C-C chemokine receptor type 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed