BDBM50166788 1-{2-[2-(4-Chloro-phenyl)-thiazol-4-ylmethoxy]-3-methoxy-benzyl}-azocane::CHEMBL197304

SMILES COc1cccc(CN2CCCCCCC2)c1OCc1csc(n1)-c1ccc(Cl)cc1

InChI Key InChIKey=UNPJHTCCHUDIIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166788   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166788(1-{2-[2-(4-Chloro-phenyl)-thiazol-4-ylmethoxy]-3-m...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibitory concentration against displacement of 35[S] MK-499 binding to hERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50166788(1-{2-[2-(4-Chloro-phenyl)-thiazol-4-ylmethoxy]-3-m...)
Affinity DataIC50: 3.80E+3nMAssay Description:In vitro inhibitory concentration against Na v1.7 channel expressed in HEK293 cells using Voltage/Ion Probe Reader (VIPR) assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed