BDBM50167613 (2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL190563

SMILES Cc1ccccc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC(C)(C)[C@@H]1C(=O)NO

InChI Key InChIKey=BHRJTBRTTVQRNI-XLIONFOSSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50167613   

TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167613((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(2-methyl-benz...)
Affinity DataIC50:  690nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-1 (MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50167613((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(2-methyl-benz...)
Affinity DataIC50:  7.30nMAssay Description:Inhibitory concentration against TNF-alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50167613((2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(2-methyl-benz...)
Affinity DataIC50:  14nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-13 (MMP-13)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed