BDBM50168639 3-Amino-N-((R)-1-(2,4-dichloro-benzyl)-2-oxo-2-{4-[1-(phenylacetylamino-methyl)-cyclohexyl]-piperazin-1-yl}-ethyl)-propionamide::CHEMBL185862

SMILES NCCC(=O)N[C@H](Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)C1(CNC(=O)Cc2ccccc2)CCCCC1

InChI Key InChIKey=HHHGGOMKUAYOJZ-HHHXNRCGSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50168639   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50168639(3-Amino-N-((R)-1-(2,4-dichloro-benzyl)-2-oxo-2-{4-...)
Affinity DataKi:  6.40nMAssay Description:Inhibition of [125I]-AgRP(83¿132) (radioligand) binding to the hMC4R stably expressed in HEK293 cells; More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50168639(3-Amino-N-((R)-1-(2,4-dichloro-benzyl)-2-oxo-2-{4-...)
Affinity DataKi:  8.80nMAssay Description:Inhibition of [125I]-AgRP(83132) (radioligand) binding to the hMC4R stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50168639(3-Amino-N-((R)-1-(2,4-dichloro-benzyl)-2-oxo-2-{4-...)
Affinity DataKi:  710nMAssay Description:Inhibition of [125I]-NDP-MSH (radioligand) binding to the human MC3R stably expressed in HEK293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50168639(3-Amino-N-((R)-1-(2,4-dichloro-benzyl)-2-oxo-2-{4-...)
Affinity DataKi:  920nMAssay Description:Inhibition of [125I]NDP-MSH (radioligand) binding to the human MC5R stably expressed in HEK293 cells More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed