BDBM50168750 (2R,3R)-3-Hydroxy-3-methyl-1-[4-(pyrazin-2-ylmethoxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL187141

SMILES C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2cnccn2)cc1

InChI Key InChIKey=GVLVYQFIEXXQOS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168750   

LigandPNGBDBM50168750((2R,3R)-3-Hydroxy-3-methyl-1-[4-(pyrazin-2-ylmetho...)
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50168750((2R,3R)-3-Hydroxy-3-methyl-1-[4-(pyrazin-2-ylmetho...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration against MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed