BDBM50168754 (2R,3R)-3-Hydroxy-3-methyl-1-[4-(pyridin-4-ylmethoxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL365247

SMILES C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccncc2)cc1

InChI Key InChIKey=DOOZILOLHOKUGO-PKOBYXMFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50168754   

LigandPNGBDBM50168754((2R,3R)-3-Hydroxy-3-methyl-1-[4-(pyridin-4-ylmetho...)
Affinity DataIC50:  7.10nMAssay Description:Inhibitory concentration against TNF-alpha release in LPS treated whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50168754((2R,3R)-3-Hydroxy-3-methyl-1-[4-(pyridin-4-ylmetho...)
Affinity DataIC50:  191nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50168754((2R,3R)-3-Hydroxy-3-methyl-1-[4-(pyridin-4-ylmetho...)
Affinity DataIC50:  190nMAssay Description:Inhibitory concentration against MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed