BDBM50168778 3-(1-Allyl-3-tert-butylsulfanyl-5-isopropyl-1H-indol-2-yl)-2,2-dimethyl-propionic acid::CHEMBL181986

SMILES CC(C)c1ccc2n(CC=C)c(CC(C)(C)C(O)=O)c(SC(C)(C)C)c2c1

InChI Key InChIKey=AEXAVZDAYSGECH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50168778   

TargetProstaglandin E synthase 2(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50168778(3-(1-Allyl-3-tert-butylsulfanyl-5-isopropyl-1H-ind...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibitory concentration against human prostaglandin E2 synthase (mPGES-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50168778(3-(1-Allyl-3-tert-butylsulfanyl-5-isopropyl-1H-ind...)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human microsomal PGES1 in cell-free system assessed as inhibition of conversion of PGH2 to PGE2 by HPLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed