BDBM50169230 (S)-(5-Chloro-3-ethyl-2-oxo-7-propyl-2,3-dihydro-benzooxazol-6-yloxy)-(4-isopropyl-phenyl)-acetic acid::CHEMBL371778

SMILES CCCc1c(O[C@H](C(O)=O)c2ccc(cc2)C(C)C)c(Cl)cc2n(CC)c(=O)oc12

InChI Key InChIKey=NIUAMYAEHXOIEB-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50169230   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169230BDBM50169230((S)-(5-Chloro-3-ethyl-2-oxo-7-propyl-2,3-dihydro-b...)
Affinity DataEC50:  360nMAssay Description:Agonist response against human PPAR gamma in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169230BDBM50169230((S)-(5-Chloro-3-ethyl-2-oxo-7-propyl-2,3-dihydro-b...)
Affinity DataIC50: 520nMAssay Description:In vitro binding affinity for human PPAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50169230BDBM50169230((S)-(5-Chloro-3-ethyl-2-oxo-7-propyl-2,3-dihydro-b...)
Affinity DataIC50: 1.41E+3nMAssay Description:In vitro binding affinity for human PPAR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed