BDBM50169236 (S)-(2-Methyl-3-oxo-5,7-dipropyl-2,3-dihydro-benzo[d]isoxazol-6-yloxy)-phenyl-acetic acid::CHEMBL427530

SMILES CCCc1cc2c(on(C)c2=O)c(CCC)c1O[C@H](C(O)=O)c1ccccc1

InChI Key InChIKey=LODDUXNJHHRABT-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50169236   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169236((S)-(2-Methyl-3-oxo-5,7-dipropyl-2,3-dihydro-benzo...)
Affinity DataEC50:  390nMAssay Description:Agonist response against human PPAR gamma in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169236((S)-(2-Methyl-3-oxo-5,7-dipropyl-2,3-dihydro-benzo...)
Affinity DataEC50:  670nMAssay Description:Agonist response against human PPAR alpha in transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169236((S)-(2-Methyl-3-oxo-5,7-dipropyl-2,3-dihydro-benzo...)
Affinity DataIC50: 850nMAssay Description:In vitro binding affinity for human PPAR alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169236((S)-(2-Methyl-3-oxo-5,7-dipropyl-2,3-dihydro-benzo...)
Affinity DataIC50: 3.80E+3nMAssay Description:In vitro binding affinity for human PPAR gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed