BDBM50169492 (R)-3,3-dimethyl-1-(5-(4-(trifluoromethyl)phenyl)-1,3,4-oxadiazol-2-yl)butan-2-yl(S)-1,2-dioxo-1-((R)-1-phenylethylamino)heptan-3-ylcarbamate::CHEMBL363773::[(S)-1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid (R)-2,2-dimethyl-1-[5-(4-trifluoromethyl-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-propyl ester

SMILES CCCC[C@H](NC(=O)O[C@H](Cc1nnc(o1)-c1ccc(cc1)C(F)(F)F)C(C)(C)C)C(=O)C(=O)N[C@H](C)c1ccccc1

InChI Key InChIKey=VZYZUCSJVPOQDE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50169492   

TargetCathepsin K(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50169492([(S)-1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbami...)
Affinity DataIC50: 0.407nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetCathepsin K(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50169492([(S)-1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbami...)
Affinity DataIC50: 410nMAssay Description:Inhibition of 10 lM Cbz-Phe-Arg-AMC binding to human cathepsin K in fluorescence assay with 100 mM NaOAcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169492([(S)-1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbami...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of 10 lM Cbz-Val-Val-Arg-AMC binding to human cathepsin S in fluorescence assay with 100 mM NaOAcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin L2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169492([(S)-1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbami...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 2 lM Cbz-Phe-Arg-AMC binding to human cathepsin V activity in fluorescence assay with 100 mM NaOAcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169492([(S)-1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbami...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of 10 lM Cbz-Phe-Arg-AMC binding to human cathepsin B activity in fluorescence assay with 100 mM NaOAcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50169492([(S)-1-(1-Phenyl-ethylaminooxalyl)-pentyl]-carbami...)
Affinity DataIC50: 1.90E+5nMAssay Description:Inhibition of 5 lM Cbz-Phe-Arg-AMC bindign to human cathepsin L activity in fluorescence assay with 100 mM NaOAcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed