BDBM50169848 1-[2-(2,4-Difluoro-phenyl)-ethyl]-4-fluoro-4-(3-fluoro-benzenesulfonyl)-piperidine::CHEMBL177401

SMILES Fc1cccc(c1)S(=O)(=O)C1(F)CCN(CCc2ccc(F)cc2F)CC1

InChI Key InChIKey=NJDSCCWXSSWOKI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50169848   

Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169848(1-[2-(2,4-Difluoro-phenyl)-ethyl]-4-fluoro-4-(3-fl...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity against human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169848(1-[2-(2,4-Difluoro-phenyl)-ethyl]-4-fluoro-4-(3-fl...)
Affinity DataKi:  49nMAssay Description:Binding affinity against human 5-hydroxytryptamine 2c receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169848(1-[2-(2,4-Difluoro-phenyl)-ethyl]-4-fluoro-4-(3-fl...)
Affinity DataKi:  791nMAssay Description:Binding affinity against human Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50169848(1-[2-(2,4-Difluoro-phenyl)-ethyl]-4-fluoro-4-(3-fl...)
Affinity DataKi:  1.53E+3nMAssay Description:Binding affinity against human IKr channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed